Amanda worked with the Tiffin lab, especially Tuomas Hamala, to analyze transcriptomes from across the north-south extent of the geographic range of common ragweed. They identified loci bearing footprints of local adaptation, and then use genotype-expression mapping and co-expression networks to infer the connectivity of the genes. The results indicate that the putatively adaptive loci are highly pleiotropic, as they are more likely than expected to affect the expression of other genes, and they reside in central positions within the gene networks. 

Hämälä, T., A.J. Gorton, D.A. Moeller, & P. Tiffin. 2020. Pleiotropy facilitates local adaptation to distant optima in common ragweed (Ambrosia artemisiifolia). PLoS Genetics 16:e1008707. pdf

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